Find the exact wire gauge you need for your specific electrical load.
Quick Answer
A 20 Amp circuit (typical for mini-splits with ~16A MCA) requires #12 Copper wire.
Most ampacity calculators ask "How many amps can this wire carry?" This tool does the opposite: "I have a 40 Amp load, what wire do I buy?" It finds the smallest wire size from NEC 310.16 where the ampacity meets or exceeds your load.